CRISPR gene editing can cause hundreds of unintended mutations
While people were initially excited about the possibilities of CRISPR technology, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.1 “‘We feel it’s critical that the scientific community consider the potential hazards of all off-target mutations caused by CRISPR, including single nucleotide mutations and mutations in non-coding regions of the genome,’ says co-author Stephen Tsang, MD, PhD, the Laszlo T. Bito Associate Professor of Ophthalmology and associate professor of pathology and cell biology at Columbia University Medical Center and in Columbia’s Institute of Genomic Medicine and the Institute of...
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